Medicine
Respiratory Medicine
Which complication or major adverse outcome is particularly associated with Acute pulmonary embolism?
A. Pulmonary hypertension and chronic respiratory failure
B. Systemic hypertension and cardiovascular risk
C. Obstructive shock from right ventricular failure
D. Severe acute asthma with respiratory failure
Correct Answer: C
A large PE can acutely raise pulmonary vascular resistance and cause right-heart failure and shock.
Medicine
Respiratory Medicine
A patient is diagnosed with Acute pulmonary embolism. Which is the most appropriate management principle?
A. Treat the underlying cause and drain the effusion when large, infected or causing significant symptoms
B. Start anticoagulation when PE is confirmed or strongly suspected and bleeding risk is acceptable; use reperfusion therapy for selected unstable patients
C. Identify and remove reversible causes and use subtype-specific specialist therapy
D. Use weight-management measures and positive airway pressure therapy when indicated
Correct Answer: B
Anticoagulation prevents clot extension; hemodynamic collapse may require urgent reperfusion.
Medicine
Respiratory Medicine
In a patient with suspected Acute pulmonary embolism, which investigation or diagnostic approach is most appropriate at this stage?
A. Risk-stratified evaluation using clinical probability, D-dimer when appropriate and CT pulmonary angiography when indicated
B. Clinical diagnosis; do not wait for chest imaging in an unstable patient
C. Thoracic ultrasound and diagnostic thoracentesis when the effusion is new, unexplained or clinically indicated
D. High-resolution CT chest with pulmonary-function testing
Correct Answer: A
Testing should follow pretest probability to avoid unnecessary imaging while rapidly diagnosing high-risk disease.
Medicine
Respiratory Medicine
A patient develops sudden dyspnea and pleuritic chest pain with tachycardia after recent immobilization. What is the most likely diagnosis?
A. Community-acquired pneumonia
B. Tension pneumothorax
C. Pleural effusion
D. Acute pulmonary embolism
Correct Answer: D
Acute unexplained dyspnea with pleuritic pain and thromboembolic risk factors suggests pulmonary embolism.
Medicine
Respiratory Medicine
Which finding most strongly supports bacterial pneumonia rather than uncomplicated viral upper-respiratory infection?
A. Isolated sneezing
B. Clear rhinorrhea alone
C. New focal lung infiltrate with systemic lower-respiratory symptoms
D. Itchy eyes without cough
Correct Answer: C
Pneumonia requires lower-respiratory involvement and usually radiographic parenchymal abnormality.
Medicine
Respiratory Medicine
Which complication or major adverse outcome is particularly associated with Community-acquired pneumonia?
A. Severe acute asthma with respiratory failure
B. Parapneumonic effusion or empyema
C. Acute hypercapnic respiratory failure
D. Obstructive shock from right ventricular failure
Correct Answer: B
Pneumonia can extend into the pleural space and cause infected fluid requiring drainage.
Medicine
Respiratory Medicine
A patient is diagnosed with Community-acquired pneumonia. Which is the most appropriate management principle?
A. Start appropriate empiric antibiotics based on severity, comorbidity and local resistance patterns
B. Use weight-management measures and positive airway pressure therapy when indicated
C. Use an inhaled corticosteroid-containing treatment strategy and provide a reliever appropriate to the regimen
D. Use short-acting bronchodilators, systemic corticosteroids and controlled oxygen; give antibiotics when bacterial features are present
Correct Answer: A
Antibiotic selection depends on setting and risk; supportive oxygen and fluids are added as needed.
Medicine
Respiratory Medicine
In a patient with suspected Community-acquired pneumonia, which investigation or diagnostic approach is most appropriate at this stage?
A. High-resolution CT chest with pulmonary-function testing
B. Sleep study or validated home sleep apnea testing in an appropriate patient
C. Spirometry demonstrating variable expiratory airflow limitation when feasible
D. Chest radiography plus severity-guided laboratory and microbiologic testing
Correct Answer: D
Chest imaging supports the diagnosis; microbiology is targeted to severity and risk factors.
Medicine
Respiratory Medicine
A patient has fever, productive cough, pleuritic chest pain and a new focal pulmonary infiltrate. What is the most likely diagnosis?
A. Pleural effusion
B. Interstitial lung disease (ILD)
C. Community-acquired pneumonia
D. Obstructive sleep apnea (OSA)
Correct Answer: C
Acute infectious respiratory symptoms plus a new infiltrate support pneumonia.
Medicine
Respiratory Medicine
Which intervention can reduce the need for intubation in appropriate COPD patients with acute hypercapnic respiratory acidosis?
A. Routine high-flow oxygen without monitoring
B. Noninvasive ventilation
C. Immediate bronchoscopy for every patient
D. Prophylactic intubation in all mild exacerbations
Correct Answer: B
Noninvasive ventilation is effective in selected acute hypercapnic COPD exacerbations with respiratory acidosis.
Medicine
Respiratory Medicine
Which complication or major adverse outcome is particularly associated with Acute exacerbation of chronic obstructive pulmonary disease (COPD)?
A. Acute hypercapnic respiratory failure
B. Obstructive shock from right ventricular failure
C. Cardiac arrest from obstructive shock
D. Empyema
Correct Answer: A
Severe exacerbations can cause ventilatory failure and respiratory acidosis.
Medicine
Respiratory Medicine
A patient is diagnosed with Acute exacerbation of chronic obstructive pulmonary disease (COPD). Which is the most appropriate management principle?
A. Start appropriate empiric antibiotics based on severity, comorbidity and local resistance patterns
B. Start anticoagulation when PE is confirmed or strongly suspected and bleeding risk is acceptable; use reperfusion therapy for selected unstable patients
C. Immediate thoracic decompression followed by definitive chest drainage
D. Use short-acting bronchodilators, systemic corticosteroids and controlled oxygen; give antibiotics when bacterial features are present
Correct Answer: D
Exacerbation therapy reduces obstruction and inflammation while avoiding excessive oxygen in patients at risk of carbon-dioxide retention.
Medicine
Respiratory Medicine
In a patient with suspected Acute exacerbation of chronic obstructive pulmonary disease (COPD), which investigation or diagnostic approach is most appropriate at this stage?
A. Spirometry demonstrating variable expiratory airflow limitation when feasible
B. Chest radiography plus severity-guided laboratory and microbiologic testing
C. Clinical assessment with oxygenation; chest imaging and blood gases when severity or an alternative diagnosis is a concern
D. Risk-stratified evaluation using clinical probability, D-dimer when appropriate and CT pulmonary angiography when indicated
Correct Answer: C
Testing is tailored to severity and helps identify pneumonia, pneumothorax, heart failure or respiratory acidosis.
Medicine
Respiratory Medicine
A patient has known COPD with increased dyspnea, cough and sputum volume or purulence. What is the most likely diagnosis?
A. Obstructive sleep apnea (OSA)
B. Acute exacerbation of chronic obstructive pulmonary disease (COPD)
C. Asthma
D. Community-acquired pneumonia
Correct Answer: B
Acute worsening of baseline respiratory symptoms beyond day-to-day variation defines a COPD exacerbation.
Medicine
Respiratory Medicine
Which finding in an acute asthma attack suggests impending respiratory failure?
A. A silent chest with exhaustion and altered mental status
B. Loud wheeze with normal speech and oxygenation
C. Mild cough after exercise only
D. Normal respiratory effort
Correct Answer: A
Reduced wheeze in a deteriorating exhausted patient may indicate critically low airflow.
Medicine
Respiratory Medicine
Which complication or major adverse outcome is particularly associated with Asthma?
A. Empyema
B. Pulmonary hypertension and chronic respiratory failure
C. Systemic hypertension and cardiovascular risk
D. Severe acute asthma with respiratory failure
Correct Answer: D
Uncontrolled bronchoconstriction and airway inflammation can progress to life-threatening ventilatory failure.
Medicine
Respiratory Medicine
A patient is diagnosed with Asthma. Which is the most appropriate management principle?
A. Immediate thoracic decompression followed by definitive chest drainage
B. Treat the underlying cause and drain the effusion when large, infected or causing significant symptoms
C. Use an inhaled corticosteroid-containing treatment strategy and provide a reliever appropriate to the regimen
D. Identify and remove reversible causes and use subtype-specific specialist therapy
Correct Answer: C
Modern asthma care includes anti-inflammatory therapy rather than relying on short-acting bronchodilator monotherapy.
Medicine
Respiratory Medicine
In a patient with suspected Asthma, which investigation or diagnostic approach is most appropriate at this stage?
A. Risk-stratified evaluation using clinical probability, D-dimer when appropriate and CT pulmonary angiography when indicated
B. Spirometry demonstrating variable expiratory airflow limitation when feasible
C. Clinical diagnosis; do not wait for chest imaging in an unstable patient
D. Thoracic ultrasound and diagnostic thoracentesis when the effusion is new, unexplained or clinically indicated
Correct Answer: B
Objective demonstration of variable airflow obstruction supports the diagnosis and helps avoid overdiagnosis.
Medicine
Respiratory Medicine
A patient has episodic wheeze, cough and chest tightness with variable airflow limitation. What is the most likely diagnosis?
A. Asthma
B. Community-acquired pneumonia
C. Acute pulmonary embolism
D. Tension pneumothorax
Correct Answer: A
Variable respiratory symptoms and variable expiratory airflow limitation are characteristic of asthma.
Medicine
Oncology
Which electrolyte abnormality is typical of tumor lysis syndrome?
A. Persistent hypophosphatemia as the rule
B. Isolated hypernatremia only
C. Severe hypouricemia
D. Hyperkalemia
Correct Answer: D
Tumor lysis classically causes hyperkalemia, hyperphosphatemia, hyperuricemia and secondary hypocalcemia.