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Medicine MCQs With Answers

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Medicine Respiratory Medicine
Which complication or major adverse outcome is particularly associated with Obstructive sleep apnea (OSA)?
A. Cardiac arrest from obstructive shock
B. Empyema
C. Systemic hypertension and cardiovascular risk
D. Pulmonary hypertension and chronic respiratory failure
Correct Answer: C
Untreated OSA is associated with hypertension, arrhythmia and broader cardiovascular risk.
Medicine Respiratory Medicine
A patient is diagnosed with Obstructive sleep apnea (OSA). Which is the most appropriate management principle?
A. Start anticoagulation when PE is confirmed or strongly suspected and bleeding risk is acceptable; use reperfusion therapy for selected unstable patients
B. Use weight-management measures and positive airway pressure therapy when indicated
C. Immediate thoracic decompression followed by definitive chest drainage
D. Treat the underlying cause and drain the effusion when large, infected or causing significant symptoms
Correct Answer: B
CPAP is highly effective for clinically significant OSA, alongside risk-factor treatment.
Medicine Respiratory Medicine
In a patient with suspected Obstructive sleep apnea (OSA), which investigation or diagnostic approach is most appropriate at this stage?
A. Sleep study or validated home sleep apnea testing in an appropriate patient
B. Chest radiography plus severity-guided laboratory and microbiologic testing
C. Risk-stratified evaluation using clinical probability, D-dimer when appropriate and CT pulmonary angiography when indicated
D. Clinical diagnosis; do not wait for chest imaging in an unstable patient
Correct Answer: A
Objective sleep testing quantifies respiratory events and confirms OSA.
Medicine Respiratory Medicine
A patient has loud snoring, witnessed apneas, obesity and excessive daytime sleepiness. What is the most likely diagnosis?
A. Acute exacerbation of chronic obstructive pulmonary disease (COPD)
B. Community-acquired pneumonia
C. Acute pulmonary embolism
D. Obstructive sleep apnea (OSA)
Correct Answer: D
Nocturnal upper-airway obstruction causes repeated apneas, sleep fragmentation and daytime symptoms.
Medicine Respiratory Medicine
Which pulmonary-function pattern is typical of many interstitial lung diseases?
A. Purely increased total lung capacity with normal diffusion
B. Isolated upper-airway obstruction only
C. Restrictive defect with reduced diffusion capacity
D. Normal lung volumes in every case
Correct Answer: C
Fibrotic interstitial lung disease commonly reduces lung volumes and gas diffusion.
Medicine Respiratory Medicine
Which complication or major adverse outcome is particularly associated with Interstitial lung disease (ILD)?
A. Systemic hypertension and cardiovascular risk
B. Pulmonary hypertension and chronic respiratory failure
C. Severe acute asthma with respiratory failure
D. Acute hypercapnic respiratory failure
Correct Answer: B
Progressive fibrosis can cause severe gas-exchange impairment and secondary pulmonary vascular disease.
Medicine Respiratory Medicine
A patient is diagnosed with Interstitial lung disease (ILD). Which is the most appropriate management principle?
A. Identify and remove reversible causes and use subtype-specific specialist therapy
B. Treat the underlying cause and drain the effusion when large, infected or causing significant symptoms
C. Use weight-management measures and positive airway pressure therapy when indicated
D. Use an inhaled corticosteroid-containing treatment strategy and provide a reliever appropriate to the regimen
Correct Answer: A
ILD treatment differs by cause; exposures, autoimmune disease and fibrotic subtypes require distinct management.
Medicine Respiratory Medicine
In a patient with suspected Interstitial lung disease (ILD), which investigation or diagnostic approach is most appropriate at this stage?
A. Clinical diagnosis; do not wait for chest imaging in an unstable patient
B. Thoracic ultrasound and diagnostic thoracentesis when the effusion is new, unexplained or clinically indicated
C. Sleep study or validated home sleep apnea testing in an appropriate patient
D. High-resolution CT chest with pulmonary-function testing
Correct Answer: D
HRCT characterizes interstitial patterns, while PFTs quantify restrictive impairment and diffusion abnormality.
Medicine Respiratory Medicine
A patient has progressive exertional dyspnea, dry cough, fine bibasal inspiratory crackles and restrictive pulmonary physiology. What is the most likely diagnosis?
A. Acute pulmonary embolism
B. Tension pneumothorax
C. Interstitial lung disease (ILD)
D. Pleural effusion
Correct Answer: C
Progressive restrictive respiratory symptoms with fine crackles suggest interstitial lung disease.
Medicine Respiratory Medicine
Which physical-examination percussion note is classically associated with a large pleural effusion?
A. Hyperresonance
B. Stony dullness
C. Tympany over the entire hemithorax
D. Normal resonance with bronchial breathing only
Correct Answer: B
Pleural fluid dampens percussion and classically produces a stony-dull note.
Medicine Respiratory Medicine
Which complication or major adverse outcome is particularly associated with Pleural effusion?
A. Empyema
B. Acute hypercapnic respiratory failure
C. Parapneumonic effusion or empyema
D. Obstructive shock from right ventricular failure
Correct Answer: A
Infected pleural fluid can become loculated and require chest-tube drainage.
Medicine Respiratory Medicine
A patient is diagnosed with Pleural effusion. Which is the most appropriate management principle?
A. Use an inhaled corticosteroid-containing treatment strategy and provide a reliever appropriate to the regimen
B. Use short-acting bronchodilators, systemic corticosteroids and controlled oxygen; give antibiotics when bacterial features are present
C. Start appropriate empiric antibiotics based on severity, comorbidity and local resistance patterns
D. Treat the underlying cause and drain the effusion when large, infected or causing significant symptoms
Correct Answer: D
Management depends on cause, size, symptoms and whether the pleural space is infected.
Medicine Respiratory Medicine
In a patient with suspected Pleural effusion, which investigation or diagnostic approach is most appropriate at this stage?
A. Sleep study or validated home sleep apnea testing in an appropriate patient
B. Spirometry demonstrating variable expiratory airflow limitation when feasible
C. Thoracic ultrasound and diagnostic thoracentesis when the effusion is new, unexplained or clinically indicated
D. Clinical assessment with oxygenation; chest imaging and blood gases when severity or an alternative diagnosis is a concern
Correct Answer: C
Pleural-fluid analysis helps distinguish transudative from exudative causes and identifies infection or malignancy.
Medicine Respiratory Medicine
A patient has dyspnea with reduced breath sounds, stony dull percussion and a meniscus on chest imaging. What is the most likely diagnosis?
A. Interstitial lung disease (ILD)
B. Pleural effusion
C. Obstructive sleep apnea (OSA)
D. Asthma
Correct Answer: B
The examination and imaging pattern is typical of pleural fluid accumulation.
Medicine Respiratory Medicine
What is the key management principle in an unstable patient with suspected tension pneumothorax?
A. Treat immediately without waiting for radiographic confirmation
B. Wait for CT chest before intervention
C. Give oral antibiotics and observe
D. Schedule outpatient spirometry
Correct Answer: A
Tension pneumothorax is a clinical emergency where decompression must not be delayed by imaging.
Medicine Respiratory Medicine
Which complication or major adverse outcome is particularly associated with Tension pneumothorax?
A. Obstructive shock from right ventricular failure
B. Empyema
C. Pulmonary hypertension and chronic respiratory failure
D. Cardiac arrest from obstructive shock
Correct Answer: D
Rising intrathoracic pressure impairs venous return and cardiac output.
Medicine Respiratory Medicine
A patient is diagnosed with Tension pneumothorax. Which is the most appropriate management principle?
A. Start appropriate empiric antibiotics based on severity, comorbidity and local resistance patterns
B. Start anticoagulation when PE is confirmed or strongly suspected and bleeding risk is acceptable; use reperfusion therapy for selected unstable patients
C. Immediate thoracic decompression followed by definitive chest drainage
D. Treat the underlying cause and drain the effusion when large, infected or causing significant symptoms
Correct Answer: C
Emergency decompression relieves obstructive pressure; tube thoracostomy provides definitive drainage.
Medicine Respiratory Medicine
In a patient with suspected Tension pneumothorax, which investigation or diagnostic approach is most appropriate at this stage?
A. Clinical assessment with oxygenation; chest imaging and blood gases when severity or an alternative diagnosis is a concern
B. Clinical diagnosis; do not wait for chest imaging in an unstable patient
C. Chest radiography plus severity-guided laboratory and microbiologic testing
D. Risk-stratified evaluation using clinical probability, D-dimer when appropriate and CT pulmonary angiography when indicated
Correct Answer: B
Tension physiology requires immediate decompression because imaging delay can be fatal.
Medicine Respiratory Medicine
A patient has sudden respiratory distress, hypotension, unilateral absent breath sounds and distended neck veins after chest trauma. What is the most likely diagnosis?
A. Tension pneumothorax
B. Asthma
C. Acute exacerbation of chronic obstructive pulmonary disease (COPD)
D. Community-acquired pneumonia
Correct Answer: A
Shock plus unilateral absent breath sounds in the right context is a clinical diagnosis of tension pneumothorax.
Medicine Respiratory Medicine
Which bedside finding in acute PE suggests higher-risk disease?
A. Normal blood pressure and no RV strain
B. Isolated mild sore throat
C. Chronic stable eczema
D. Hypotension with signs of right ventricular strain
Correct Answer: D
Hemodynamic instability and right ventricular dysfunction identify more severe pulmonary embolism.
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