CSS - PMS - CCE - PCS - General Science
Blood System
During fetal life, a major organ of hematopoiesis is the:
A. Liver
B. Stomach
C. Lung
D. Thyroid
Correct Answer: A
The fetal liver is a major hematopoietic organ before bone marrow becomes dominant.
CSS - PMS - CCE - PCS - General Science
Blood System
The earliest major site of blood cell formation in the human embryo is the:
A. Thymus
B. Yolk sac
C. Kidney
D. Pancreas
Correct Answer: B
Early embryonic hematopoiesis begins in the yolk sac before shifting mainly to the liver and later bone marrow.
CSS - PMS - CCE - PCS - General Science
Blood System
The stem cell from which all blood cells ultimately arise is the:
A. Myoblast
B. Hematopoietic stem cell
C. Osteoblast
D. Fibroblast
Correct Answer: B
All formed elements of blood originate from multipotent hematopoietic stem cells in bone marrow.
CSS - PMS - CCE - PCS - General Science
Blood System
Red blood cells are produced primarily in adults in the:
A. Yellow bone marrow
B. Red bone marrow
C. Liver only
D. Spleen only
Correct Answer: B
In adults, erythrocytes are formed mainly in red bone marrow of the axial skeleton and proximal ends of some long bones.
CSS - PMS - CCE - PCS - General Science
Blood System
Which ion is the major intracellular cation of blood cells?
A. Sodium
B. Potassium
C. Chloride
D. Bicarbonate
Correct Answer: B
Potassium is the major intracellular cation, including within blood cells.
CSS - PMS - CCE - PCS - General Science
Blood System
Which ion is the major cation of blood plasma?
A. Potassium
B. Calcium
C. Sodium
D. Magnesium
Correct Answer: C
Sodium is the major extracellular cation and therefore the predominant cation in plasma.
CSS - PMS - CCE - PCS - General Science
Blood System
The principal buffer system of blood plasma is the:
A. Phosphate buffer only
B. Bicarbonate buffer system
C. Ammonia buffer system
D. Lactate buffer system
Correct Answer: B
The carbonic acid-bicarbonate system is the principal extracellular buffer system in blood.
CSS - PMS - CCE - PCS - General Science
Blood System
The normal pH of arterial blood is approximately:
A. 6.8–7.0
B. 7.00–7.20
C. 7.35–7.45
D. 7.60–7.80
Correct Answer: C
Normal arterial blood pH is tightly regulated around 7.35–7.45.
CSS - PMS - CCE - PCS - General Science
Blood System
Antibodies are mainly found in which plasma protein fraction?
A. Alpha globulins
B. Beta globulins
C. Gamma globulins
D. Albumin
Correct Answer: C
Immunoglobulins are concentrated mainly in the gamma-globulin fraction of plasma proteins.
CSS - PMS - CCE - PCS - General Science
Blood System
A major function of plasma albumin is to:
A. Destroy bacteria directly
B. Maintain colloid osmotic pressure
C. Carry oxygen in red cells
D. Produce platelets
Correct Answer: B
Albumin helps retain water within the vascular compartment by maintaining plasma oncotic pressure.
CSS - PMS - CCE - PCS - General Science
Blood System
The most abundant protein in human plasma is:
A. Globulin
B. Albumin
C. Fibrin
D. Hemoglobin
Correct Answer: B
Albumin is the most abundant plasma protein and is a major contributor to plasma colloid osmotic pressure.
CSS - PMS - CCE - PCS - General Science
Blood System
Plasma differs from serum mainly because plasma contains:
A. Glucose
B. Electrolytes
C. Clotting factors such as fibrinogen
D. Antibodies only
Correct Answer: C
Serum is plasma after clotting has occurred, so it lacks fibrinogen and several clotting factors consumed in the clotting process.
CSS - PMS - CCE - PCS - General Science
Blood System
The percentage of blood volume occupied by red blood cells is called:
A. ESR
B. Hematocrit
C. Clotting time
D. Osmotic index
Correct Answer: B
Hematocrit, also called packed cell volume, is the percentage of whole blood occupied by red blood cells.
CSS - PMS - CCE - PCS - General Science
Blood System
Approximately what fraction of whole blood is plasma by volume?
A. About 35%
B. About 45%
C. About 55%
D. About 75%
Correct Answer: C
Plasma normally forms about 55% of whole blood volume, while formed elements account for roughly 45%.
CSS - PMS - CCE - PCS - General Science
Blood System
Incompatible red-cell transfusion can cause:
A. Bile production
B. Agglutination and hemolysis
C. Bone formation
D. Osmosis only
Correct Answer: B
Antigen-antibody reactions can clump and destroy RBCs.
CSS - PMS - CCE - PCS - General Science
Blood System
The Rh factor most commonly refers to antigen:
A. A
B. D
C. B
D. H
Correct Answer: B
Rh status is primarily defined by D antigen.
CSS - PMS - CCE - PCS - General Science
Blood System
Vitamin K is especially important for normal synthesis of several:
A. Thyroid hormones
B. Antibodies
C. Digestive enzymes
D. Clotting factors
Correct Answer: D
Vitamin K supports clotting-factor synthesis.
CSS - PMS - CCE - PCS - General Science
Blood System
The mesh protein that stabilizes a blood clot is:
A. Actin
B. Albumin
C. Globulin
D. Fibrin
Correct Answer: D
Fibrin forms the clot mesh.
CSS - PMS - CCE - PCS - General Science
Blood System
The process that stops bleeding after vessel injury is called:
A. Phagocytosis
B. Hematopoiesis
C. Hemostasis
D. Hemolysis
Correct Answer: C
Hemostasis stops bleeding.
CSS - PMS - CCE - PCS - General Science
Blood System
A reduction in hemoglobin concentration below normal is termed:
A. Leukemia
B. Thrombosis
C. Anemia
D. Polycythemia
Correct Answer: C
Anemia reduces oxygen-carrying capacity.